GHK-Cu
The copper peptide your own plasma makes less of every decade
CAS 49557-75-7$85.00
GHK-Cu
CAS 49557-75-7$85.00
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A copper-binding tripeptide studied for skin-regeneration, hair, and anti-aging research.
- Ships fast from the US
- Batch number on every vial
- ≥99% HPLC purity target
Before ordering
- For laboratory research use only — not for human or veterinary use.
- Every vial carries a batch number (see Batch Information below).
- Read the Shipping Policy and Refund Policy before ordering.
Research Overview
The copper peptide your own plasma makes less of every decade
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine — discovered in 1973 and studied for five decades since. Circulating levels decline sharply with age, which is one reason it became a fixture of skin-remodeling and regenerative research. Uniquely on this list, GHK-Cu has substantial human data — though almost all of it involves topical, cosmetic use.
Collagen synthesis & skin remodeling
Early human trialsThe classic finding: GHK-Cu stimulates collagen synthesis in cultured fibroblasts. Decades of follow-on work — including controlled human studies of topical copper-peptide formulations — report improvements in skin density, firmness, and photoaging markers.
Wound healing
Preclinical (cell & animal)In animal wound models, GHK-Cu accelerated healing and increased blood-vessel formation at the wound site, consistent with its collagen and glycosaminoglycan-stimulating activity.
Gene-expression modulation
Preclinical (cell & animal)Gene-profiling work suggests GHK affects the expression of a surprisingly large fraction of the human genome, shifting expression patterns toward those seen in healthier, younger tissue — a bold claim that remains to be independently validated at scale.
Antioxidant & anti-inflammatory actions
Preclinical (cell & animal)GHK-Cu shows anti-inflammatory and antioxidant activity in tissue models, including suppression of inflammatory cytokines after injury — one proposed mechanism for its skin-calming reputation in cosmetic use.
The human evidence is overwhelmingly topical and cosmetic. Systemic (injectable) GHK-Cu has very little published human data.
Technical Specifications
- CAS Number
- 49557-75-7
- Formula
- C14H22CuN6O4
- Molecular Weight
- 403.9 g/mol
- Sequence
- Gly-His-Lys · Cu2+
- Purity Target
- ≥99% (HPLC)
- Appearance
- White lyophilized powder
- Vial Size
- 100 mg
- Solubility
- Soluble in bacteriostatic water and sterile water.
- Storage
- Lyophilized: store at -20 C, protected from light. Reconstituted: 2-8 C, use within 28 days.
- Handling
- For laboratory research use only. Handle aseptically and avoid repeated freeze-thaw cycles.
Why RGP
We're deliberately not the cheapest vial on the market. Every batch is manufactured to a ≥99% HPLC purity target, batch-tracked from manufacture to your bench, and shipped fast from the US with full specifications on record. Independent third-party testing is underway — results will be published here as they come in.
